Synthesis and antimicrobial activity of new polyfunctionally substituted pyridines and their fused derivatives
نویسنده
چکیده
Ethyl pyruvate (EP) on reacting with malononitrile or isothiocyanates gives the pyridine derivati ves 5 and 9a , b , respecti vely. Chalcone deri vati ve of EP reacts with malononitrile to yield the pyran derivative which in turn IS transformed into pyridine derivative 14. Reactivity of 5 and 9a towards di fferent organic reagents has been investigated . Antimicrobial activity of some newly synthesized pyridines is also reported.
منابع مشابه
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